Methods of Diagnosis
If you suspect that you or someone you know is having a stroke or transient
ischemic attack (TIA), get to the hospital immediately so a physician can make
a diagnosis and start treatment. Besides performing a physical exam and determining
the symptoms, the physician will perform or order tests to determine the cause
of the TIA or stroke.
The physician may first order a computed tomography (CT) scan if he or she
suspects a stroke. This scan can determine whether bleeding or a vessel blockage
caused a stroke. It also is used to assess a stroke's size and location, as
well as if any brain damage has occurred.
The physician might perform a neurological examination, which includes an
assessment of the cranial nerves, motor skills, coordination and gait, reflexes,
and sensory response.
Physicians use scales of neurological impairment, including the National Institutes
of Health (NIH) stroke scales, to determine the extent of the stroke's
effect on brain function. The scales are questionnaires that rate such criteria
as how well a person responds to commands or uses language skills.
Magnetic resonance imaging (MRI), a noninvasive test that produces pictures
of the brain and its arteries, is most useful for detecting the particular area
of brain tissue that may have been damaged by ischemic stroke. An MRI also can
help determine whether a person who had a stroke also has cytotoxic edema, a
condition in which the water content in brain cells increases.
Another noninvasive test, magnetic resonance angiography (MRA), is a combination
of an MRI and an angiogram (a test that displays an x-ray of blood flow to the
brain after dye is injected into the arteries). MRA is used to detect blood
vessel changes, including blockage, narrowing, or the presence of an aneurysm.
Ultrasound transforms sound waves into electronic images. Carotid ultrasound
is used to evaluate the blood flow of the carotid arteries (located in the neck).
It shows how much these arteries have narrowed. In this procedure, a transducer
is held against the skin over the carotid artery, and it sends an ultrasound
signal to a computer that calculates how quickly the blood is moving. This enables
the physician to diagnose any blockage in the carotid arteries. Transcranial
Doppler ultrasound shows the blood traveling through the arteries to the brain,
revealing whether the arteries are narrowed or blocked.
Duplex Doppler ultrasound and arteriography are two diagnostic imaging techniques
used to determine if a person should undergo a carotid endarterectomy, in which
a surgeon removes fatty deposits from the arteries.
Ocular pneumoplethysmography (OPG) helps physicians discover if the carotid
arteries are delivering blood to the brain and the eyes.
The physician may use a cerebral angiography to determine if a TIA or a stroke
has occurred. The test uses x-rays to search for abnormalities of the arteries
that supply the brain. While the patient is under local anesthesia, the surgeon
places a thin, flexible tube in an arteryusually at the groin or elbowand
guides it to a carotid artery. When the catheter is in position, the surgeon
injects a dye through it that can be seen on x-rays. The outline of the blood
flow through the arteries is then visible on the x-ray.
During a xenon CT scan, the person inhales a mix of oxygen and xenon, and
then undergoes a CT scan. Xenon's high density increases the contrast
between areas of high and low blood flow in the brain.
The physician might order radionuclide single-photon emission CT (SPECT) scanning
to provide more information about blood flow. During this procedure, the person
either swallows or receives an injection containing a radioisotope. The radioisotope
travels to a target, where it emits radiation that's detected by a gamma
camera.
Positron emission tomography (PET) scanning is a type of radionuclide scanning
that creates an image based on the function of individual cells within the brain.
Unlike CT scanning, PET scanning doesn't produce good structural images.
Instead, it offers information about the chemical activity of tissues or organs.
It's also used to assess blood flow. PET scanning is extremely important
in determining the extent of stroke damage on the brain. On a PET scan of the
brain, red and yellow spots indicate high levels of brain activity and blue
and black areas indicate low levels of brain activity. PET scanning also can
help physicians determine whether brain cells are still chemically active and
capable of recovery or if they have died.
References
- How Does a Doctor Diagnose Stroke? American Federation for Aging Research, 2002.
- Diagnosis, American Stroke Association, 2002.
- NIH Stroke Scale, Virtual Hospital, 2003.
- MR Angiography (MRA), Radiological Society of North America, 2003.
- Carotid Ultrasound (Carotid Doppler, Carotid Duplex), Internet Stroke Center, 2003.
- Risk Reduction Through Surgery, National Stroke Association, 2002.
- Cerebral Angiography (Cerebral Angiogram, Cerebral Arteriogram, Digital Subtraction Angiography [DSA], Internet Stroke Center, 2003.
- Guide to Imaging Techniques in Stroke Diagnosis: Ultrasound, Internet Stroke Center, 2003.
- Guide to Imaging Techniques in Stroke Diagnosis: SPECT and Xenon Contrast CT, Internet Stroke Center, 2003.
- Glossary of Neurological Diagnostic Tests, American Association of Neurological Surgeons, 2003.
Source of Material: RockHill Communications,
14 Rock Hill Road Bala, Cynwyd, PA 19004, (610) 667-2040,
Writer: Christine Norris
Editors: Erin Murphy, Andrea King, Joanne Poeggel, Ron Wozny
Clinical Reviewer: Patt Panzer, M.D.
Date Written: 4/30/01
Last Revised: 4/3/03
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